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Clinical trials have shown that Retatrutides triple agonist mechanism has a favourable safety profile, with no significant safety signals identified in studies to date
The ratio of membrane versus cytosolic IGF-1R localization in the untreated panel indicates cytosolic retention of hyposialylated IGF-1R in GNE knockdown cells but not in V603L GNE mutant cells
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Faseb J 2006
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